Volume 11

Number 01 January 2021
Mixed Connective Tissue Disease- Physician’s Dilemma: A case report

DOI: https://doi.org/10.47648/jswmc2021v11-08

Abu Saleh Shimon, Mahjuba Umme Salam, Monharul Islam Bhuiyan, Mashuq Ahmad Jumma, Imran Hussain, Farzana Ahmed Bristy, Rehana Parvin

Mixed connective tissue disease is an entity of autoimmune disease with overlapping features of systemic lupus erythematosus, scleroderma, rheumatoid arthritis, dermatomyositis and with positive anti-U1 RNP antibody. We report here a 52 year old non-diabetic, normotensive woman presenting with new onset dysphagia for two months with variable features of multiple types of connective tissue diseases for two years. Clinical features and type specific serological tests for different connective tissue diseases showed puzzling results. However, finally a high titer of anti-U1RNP antibody led to the diagnosis of mixed connective tissue disease.