Volume 10

Number 01 January 2020
Emergence of SARS-CoV-2: A Review

DOI: NO DOI Assigned

Mohsina Khatoon

Background: A novel corona virus infection spread in the city of Wuhan, Hubei province, China from the Hunan seafood wholesale market, which also sold wild animals, in December 2019. The genome sequence and symptoms of infection of this virus is mostly similar to the SARS-CoV which broke out in 2002. As a result this novel corona virus has been named as SARS-CoV-2 by WHO. WHO named the disease as COVID-19 as it took the form of a pandemic. Mode of Transmission: Person to person transmission is thought to occur among close contacts mainly via respiratory droplets, aerosol and airborne when an infected person coughs or sneezes. Receptor Specificity: SARS-CoV-2 uses ACE-2 receptors to infect airway epithelial alveolar type-II pneumocyte. Conclusion: Patients of COVID-19 and SARS have similar pattern of inflammatory damage. It causes rapid transmission so countries around the world should intensify attention to the disease surveillance system.