JSWMC

Objective: To determine the pattern of electrophysiologic findings in Guillain-Barre Syndrome (GBS) patients in north-eastern Bangladeshi population. Methods: This observational study was carried out at neurophysiology laboratory in a specialized center of Sylhet with the diagnostic facility for nerve conduction study, from July 22- July 2024, Total patient was 248 . Data were collected from the patients who underwent NCS with a provisional diagnosis of GBS. Result: A total of 248 patients , mean age of 43 ± 13.24 years and a slightly male dominance (57.4%) were evaluated. Alost half of the patients (43%) reported a preceding diarrheal illness. Ascending motor paralysis was observed in majoity of the patients (86%), and 2% were identified as Miller Fischer variant. In the nerve conduction study, majority (36.7%) were found to have motor Axonal polyneuropathy involving both Peroneal nerves, followed by Motor Sensory Axonal Polyneuropathy among 34.3%. Acute motor axonal polyneuropathy (AMAN) was the most frequent subtype (60.9%), followed by Acute motor sensory axonal polyneuropathy (AMSAN) in 34.3% and Acute inflammatory demyelinating polyneuropathy (AIDP) in only 4.8%. Conclusion: GBS might have some regional variations despite having the demographic as well as clinical similarity. With AMAN being the predominant subtype, AIDP is much less common in north eastern Bangladeshi population.