DOI: N/A
Salam MU, Ahmad MM, Munim R, Saha M, Chowdhury TR, Bristy FA, Dhar P, Ferdous T, Chowdhury TA, Mohsin S, Islam A, Karmakar D, Tuli TB
Background and Objectives: Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) is a common global condition associated with metabolic dysfunction. This study investigated the relationship between ultrasound-graded MASLD severity and serum lipid levels in adults.
Methods: A total of 101 participants (32 males, 69 females) with ultrasound-diagnosed MASLD were included. Participants were categorized as Grade I (n=79), Grade II (n=21), and Grade III (n=1). Serum lipids, including total cholesterol, triglycerides, HDL, and LDL, were measured. Data were analyzed using one-way ANOVA and Pearson correlation.
Results: The mean age was 50.7±13.1 years, with a mean BMI (Body Mass Index) of 27.2±4.43 kg/m². No statistically significant differences in lipid levels were observed across MASLD grades (p>0.05). Correlation analysis showed weak, non-significant associations between MASLD grade and lipid levels, as well as between the lipid parameters.
Conclusion: Lack of significant relationship between ultrasound-graded MASLD severity and serum lipid levels, suggested that factors beyond lipid levels may contribute to disease progression.